Control and Prevention of Malaria Project (CAP-Malaria)


This project aims to prevent malaria and contain the spread of multi-drug resistant Plasmodium falciparum (P. falciparum) malaria in the Greater Mekong Subregion. P. falciparum is the most common and the most deadly parasite that causes malaria in humans. The best available treatment, particularly for P. falciparum malaria, is artemisinin-based combination therapy (ACT).

The CAP-Malaria Project is funded by United States Agency for International Development (USAID) RDMA under Cooperative Agreement Number AID-486-A-12-00001. The project team includes prime recipient University Research Co., LLC (URC) and sub-recipient organizations, including Save the Children.


The Challenge

Along with preventing malaria and containing the spread of P. falciparum, a second challenge is the quality of treatment: self-medication and poor treatment, particularly in the unregulated private sector, make it increasingly difficult to ensure proper drug use. Counterfeit and substandard antimalarial medications–which can cause death, undermine confidence in malaria treatment, and increase drug resistance–are also highly prevalent.



  • Develop and scale up cost-effective vector control interventions to prevent the transmission of malaria
  • Improve the quality and effectiveness of diagnosis and treatment of malaria at the community and health facility levels
  • Reduce management bottlenecks of national malaria control programs and local institutions to implement and monitor malaria control activities
  • Support the establishment and maintenance of strategic information for malaria control



  • Assisted the National Malaria Control Program to address the immense coverage gaps in malaria services in highly endemic areas of Cambodia by working at the community level through village malaria workers (VMWs), mobile outreach services, public health facilities, and employer-based malaria control programs, with a focus on areas with high concentrations of mobile and migrant populations.
  • Strengthened malaria service delivery systems through training VMWs, health care providers, laboratory technicians, and local community-based organizations (CBOs) as sub-grantees, equipping them with rapid diagnostics tests (RDTs), microscopes, and anti-malarial drugs, and establishing systems for ongoing supervision. Long-lasting insecticide-treated nets (LLINs) were distributed among high-risk populations and/or high-risk areas, accompanied by community mobilization to promote LLIN use, early diagnosis, and adherence to appropriate treatment.
  • In total, the project reached 226,838 people with interpersonal communication (IPC), 211,200 with small media, and 9,110 via community mobilization; updated national treatment guidelines; provided lab training including microscopy to 518 personnel; ensured no stock-outs of RDTs or artemisinin-based combination therapies (ACTs) at delivery points; conducted 13,127 monitoring visits on ITN coverage and net use; and treated 12,785 nets.
  • Worked with the Vector Borne Disease Control Division (VBDC) to build their capacity, support health system improvements, create a network of microscopists, strengthen correct use of RDTs and ACTs via quality assurance/quality control (QA/QC), and increase the availability of strategic information.
  • Established a number of surveillance sites to monitor the emerging ACT drug resistance in a number of regions in the Cambodia
  • Collaborated with various stakeholders from the MOH, NMCP, local government - respective State/Region Administration, Township & District Medical Officers (TMO/DMO), local village leaders and administrators, and with international & local NGOs implementing Regional Artemisinin Initiative (RAI) and Global Fund-Malaria projects, and with the non-state authorities in control of many of the project areas in conflict areas.


The picture shows one forest goer family who receiving the LLIN through the identified touch point in Siem Pang district of Stung Treng province.
In Cambodia, a family receives their LLIN through the identified touch point in Siem Pang district of Stung Treng province
2011 to 2016
US Agency for International Development (USAID)
Save the Children Myanmar
Kenan Institute Asia
Regions/ Countries 
Geographic Scope 
Greater Mekong Sub-region