The USAID Defeat TB project is a five-year project (2017 – 2022) that aims to increase tuberculosis (TB) case notification, case detection and treatment outcomes through health system strengthening with the aim of ending the TB epidemic in Uganda. Defeat TB will provide technical assistance to the National TB and Leprosy Programme (NTLP) to improve coordination of high impact and innovative interventions to appropriately respond to the TB epidemic in Uganda.

Defeat TB will provide direct technical assistance to the NTLP national and sub-national structures, the districts of Kampala, Wakiso and Mukono and drug resistant TB treatment sites including Mulago National Referral Hospital DR-TB unit, Arua, Soroti, Hoima, Masaka, Mubende and Fort Portal Regional Referral Hospital and any additional sites in non-USAID supported regions. Defeat TB will collaborate with regional mechanisms to provide indirect technical assistance to Mbarara, Kabale, Lira, Gulu, Iganga, Mbale, Kitgum, Matany and any additional sites in USAID supported regions.

The key Defeat TB result areas include:

  • To increase screening and detection of all forms of tuberculosis in infants, children, adolescents, and adults at facility and community levels
  • To initiate and complete treatment for all patients diagnosed with all forms of TB
  • To ensure strong community systems to support the continuum of TB prevention, screening, diagnosis, care, and treatment
  • To enhance leadership and technical capacity of the TB program at national and subnational levels to effectively guide and manage implementation of TB control activities

The key implementation strategies include:

  • Leveraging multi-stakeholder partnerships including MOH, CSOs, the private sector and communities to ensure a coordinated and unified TB response that builds on best practices, complements and avoids duplication
  • Using differentiated implementation models that recognize the need for tailored approaches for rural and urban settings
  • Strengthening the capacity for application of quality improvement methods to improve facility and community level service delivery processes and outcomes
  • Using innovative, low-cost technologies for GIS patient tracking, diagnostics, SMS for TB case notification and treatment, and mapping of TB hotspots, including DR-TB identification and treatment adherence


2017 to 2022
US Agency for International Development (USAID)
The AIDS Support Organization (TASO)
Infectious Diseases Institute (IDI)
Regions/ Countries