URC began working in Africa in 1980, expanding the service capacity of Senegal's Ministry of Health and supporting the development of a family health organization, which included training in management, information systems, and health promotion. From that point forward, URC's work in Africa expanded rapidly, and we have now worked in over 30 African countries.

Throughout the continent, we have applied innovations in systems strengthening, improvement science, and health communication and behavior change to address addressed major issues in global health  to improve the prevention, treatment, and care of people living with diseases such as HIV/AIDS, malaria, and tuberculosis. Our work to reduce maternal and child deaths through respectful, quality MNCH and family planning and reproductive health has been far reaching and continues to improve the lives of children, their families, and their communities.